EMEA | Winter 2026 Edition
Welcome to The Readout! Each quarter, we bring you essential highlights, technical updates, and resources designed to help core facilities maximize the capabilities and impact of your 10x instrumentation and assays. Let's jump right in — and happy reading.
After a standout debut in Paris, the Core Summit returns — this time in Vienna. We’re excited to build on last year’s success and bring our community together for another round of insights and connections.
This year’s summit will feature:
Curious about last year's event? Here are some highlights from the community:
"As I said during the panel discussion I joined (I got a bit of applause—so maybe the crowd agreed with me): the more empowered core facilities are, the more the technology will actually get used. We need to be able to operate at a near-FAS level. If we can troubleshoot ourselves, we’ll move faster, get better results, and vendors can scale more sustainably. In tough times, we’ve got to help each other shine."
— Catharine Aquino, Head of Genomics, Functional Genomics Center Zurich
"These are the pleasures of our work : not just selecting biological samples and conducting experiments, but also opening our minds, exchanging ideas, and get inspired by our colleagues from Europe and overseas. "
— Chiara Benedetto, Spatial transcriptomics specialist, Institut du Cerveau — Paris Brain Institute
Paris Core Excellence Summit, 2025. Left to right: Katy Vandereyken, Research Manager, KU Leuven; Catharine Aquino Fournier, Head of Genomics, Functional Genomics Center Zurich; Andreas Sommer, Head of NGS Facility, Vienna BioCenter Core Facilities; Michael Schnall-Levin, Chief Technology Officer, 10x Genomics; Katarina Tiklova, Head of the In Situ Sequencing Unit, Stockholm University; Jan-Philipp Mallm, Lab Head Single-Cell, German Cancer Research Centre
Spatial transcriptomics (ST) technologies are reshaping our understanding of tissue organization and cellular context in health and disease. However, technical benchmarking across platforms remains limited, particularly in formalin-fixed, paraffin-embedded (FFPE) clinical samples, which represent the most common tissue format in oncology.
Cervilla, S., Grases, D., Perez, E. et al. A technical comparison of spatial transcriptomics platforms across six cancer types. Genome Biol 27, 22 (2026). https://doi.org/10.1186/s13059-026-03937-y
Our congratulations to the team on this great benchmarking effort!
Visit our Knowledge Base, where our experts answer your questions. See our latest published articles answering your questions on Visium sample prep:
Xue Wu, Carolyn Morrison, Jawad Abousoud, Payam Shahi, Yinzhou Zhu, Tingsheng Yu Drennon, Shaun Jackman, Chris Macklin, Ann Renschler, Sini Reponen, Paul Lund, Peter Smibert, Andrew Kohlway, 10x Genomics
Presented at SITC 2025
We are happy to share our recently published document that demonstrates the expanded multiplexing capacity of GEM-X Flex Apex (formerly Flex v2). This document showcases:
In this edition, we are pleased to announce four new partnerships aimed to broaden the reach of our technologies. These collaborations represent an important step forward, creating new avenues for innovation and data-driven discovery.
We are excited to share that PharosAI, a UK-based research consortium, has selected our Xenium spatial platform to help build one of the world’s most comprehensive multimodal cancer datasets. This consortium brings together King's College London, Queen Mary University of London, Guy's and St Thomas' NHS Foundation Trust and Barts Health NHS Trust to transform decades of archived NHS cancer samples into high-resolution, AI-ready datasets.
PharosAI will democratize access to these datasets, making them securely available to a broad community of researchers and innovators. Read the full announcement.
Our new collaboration with BioTuring aims to address the challenge many researchers face with large multimodal datasets, where analysis — rather than data generation — is the primary bottleneck. This partnership connects our technologies with BioTuring’s advanced analytical ecosystem to better link data generation with downstream analysis. Read the full announcement.
CareDx and 10x Genomics to Launch ImmuneScape™ Program – A Multiomics Research Platform to Decode Transplant Rejection and Drug Response
Collaboration will engage leading transplant clinician-scientists to study antibody-mediated rejection (AMR) and microvascular inflammation (MVI) using cellular-resolution profiling. Read the full announcement
Cancer Research Institute Launches Transformative AI-Driven Immuno-Oncology Initiative Powered by 10x Genomics Technology
Multi-phase initiative will generate single cell and spatial data from over 20,000 samples across leading immuno-oncology laboratories to map the immune landscape of cancer and drive the next generation of immunotherapies and vaccine discovery. Read the full announcement
What fascinates me about single cell and spatial is the ability to see not only heterogeneity across cell types, but heterogeneity within cell types.
– Nigel Delaney, Vice President of Computational Biology, 10x Genomics
Bringing these approaches together—and integrating the rich, multimodal data from single cell assays into spatial frameworks—will unlock transformative insights into biological complexity.
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The tools you choose build the foundation of your single cell research success, so it’s important to make sure you’re choosing the right one. This poster is a starting point for selecting your assay, whether it’s the probe-based chemistry of Flex or the whole transcriptome profiling of the Universal portfolio.
Fill out the form to receive a print-ready, high-resolution file.
Plate-based multiplexing with Apex has transformed Flex, enabling unprecedented scale. And because it’s powered by Chromium automated cell partitioning, superior performance comes standard. The benefits of plates plus Apex:
Planning your next experiment? Check out our Experiment Builder, now available for all 10x platforms. Just specify your conditions, and the tool instantly identifies the products you’ll need.