On-Demand Webinar

Placing Single Cells at the Center of Infectious Disease Biology

Explore the latest published and pre-print infectious disease research, including studies of COVID-19, supported by single cell gene expression and immune profiling technology from 10x Genomics.


Watch this on-demand webinar recording to explore crucial applications of single cell gene expression and immune profiling for studies of COVID-19 and broader infectious disease research. Learn how scientists leveraged single cell approaches to:

  • Create single cell atlases of diverse biological systems and organs, annotating the expression of human receptor genes implicated in viral entry
  • Identify specific cell types highly susceptible to infection on the basis of quantified co-expression of genes associated with viral infection, including ACE2 and TMPRSS2
  • Resolve the immune microenvironment of infected lung tissue, distinguishing the cellular and molecular features of severe and mild cases of COVID-19, and uncovering potential novel biomarkers
  • Investigate the transcriptional programs underlying the adaptive immune cell response to vaccination, identifying both specific and non-specific expanded clonotypes
  • Map the relationship between full-length, paired T-cell and immunoglobulin sequences and antigen specificity to accelerate immune repertoire discovery and validation

Contact us if you’re ready to talk to an expert about our Immunology Solutions.
Watch this on-demand seminar recording to learn how UCSF Assistant Professor, Dr. Jimmie Ye, and his team:
  • Performed single cell RNA-sequencing for 1 million immune cells from 200 mixed blood samples from patients with lupus and healthy controls
  • Quantified cell type proportions and defined biomarkers predictive of lupus disease status and severity with single cell gene expression data
  • Optimized cellular throughput and reduced error from sample preparation with a multiplexing workflow
  • Characterized cellular and molecular variation between each unique sample, and removed doublets, using a demultiplexing algorithm
Contact us if you’re ready to talk to an expert about our Immunology Solutions.
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