A complete toolkit for FFPE
10x Genomics empowers your analysis of FFPE samples with three complementary technologies: Chromium Single Cell Gene Expression Flex, Visium CytAssist Spatial Gene Expression, and Xenium In Situ Gene Expression. Each of these assays provides a validated, reliable method for generating high-quality data from FFPE tissue, allowing you to access multiple dimensions of these precious samples and unlock new biological insights.
New insights, preserved tissues
Use your invaluable FFPE samples for retrospective studies to make new discoveries
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Direct comparisons
Integrate single cell and spatial data with matching probe sets for single cell and spatial gene expression analysis
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Increasing research impact
Advance your research with high-resolution assays that let you ask new questions, reveal new insights, and publish more frequently
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Innovation meets reliability
Be confident in your results with validated, robust FFPE protocols for single cell, spatial biology, and in situ analysis from a trusted research partner
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Explore the solutions
Single Cell
Chromium Single Cell Gene Expression Flex for FFPE
Characterize tissue heterogeneity, discover rare cell types, and dissect molecular mechanisms cell by cell.
- Obtain high-quality data using an innovative probe design that enables profiling of samples with fragmented RNA, even FFPE
- Use a sensitive, robust protocol validated across a wide range of tissue types
- Complement whole transcriptome analysis (WTA) with custom probe pairs for specific gene targets of interest
- Analyze 1 to 128 samples, or up to 1 million cells per run, with the ability to easily scale sample and cell throughput to fit your needs
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Spatial
Visium CytAssist Spatial Gene and Protein Expression for FFPE
Harness whole transcriptome discovery while defining the relationship between cellular function and location.
- Discover your tissue with unbiased whole transcriptome analysis at high spatial resolution across whole tissue sections
- Integrate spatial gene expression seamlessly with standard histology workflows for H&E and immunofluorescence (IF) staining
- Start from FFPE blocks or pre-sectioned H&E- or IF-stained FFPE tissue sections on standard glass slides
- Evaluate stained and imaged tissues to find the most biologically relevant sections and areas before continuing with the Visium workflow
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In Situ
Xenium Analyzer for FFPE
Refine and validate biological insights revealed through single cell and spatial analyses.
- Localize 100s to 1,000s of RNA targets with subcellular and single molecule resolution in FFPE sections, no tissue optimization required
- Take advantage of Xenium’s non-destructive assay to integrate standard histopathology workflows with single cell spatial imaging data
- Choose from biologically relevant and easily customizable catalog of panels, or request a fully customized standalone panel for your targets of interest
- Accelerate your studies with the ability to analyze up to 1,400 mm² of tissue per week
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FFPE Resources
Dive into the data and see how researchers are using Gene Expression Flex to bring highly sensitive single cell profiling to FFPE samples.
See how you can gain a deeper, more holistic understanding of tissue organization, using Visium CytAssist to expand FFPE sample access and ease workflows.
Learn how Xenium’s flexible compatibility and fast workflows bring high-plex in situ to FFPE sections, while maintaining tissue integrity to enable post-run staining and imaging.
Multi-dimensional analysis enables more powerful discoveries. Explore how researchers are revealing biological insights by combining single cell, spatial, and in situ data.
