Customer Research Snapshots

Customers Use Single Cell Solutions for Immunology Research

See how customers are using our immunology solutions

Introducing the Customer Research Snapshot

The Customer Research Snapshot is a document that condenses 10x Genomics customer publications into easy-to-understand experimental summaries, detailing how they performed their experiments, analysed their data and reached their conclusions. Take a look at our growing list of customer snapshots, showcasing how immunologists are using 10x Genomics single cell solutions to understand the diverse cellular and molecular mechanisms underlying the immune response.

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Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment


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The immune cell landscape in kidneys of patients with lupus nephritis
Arazi et al., Nature Immunology 2019
Performed single cell analysis of immune cells in human kidneys affected by lupus nephritis. Download →
Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment
Azizi et al., Cell 2018
Performed single cell transcriptional and immune profiling of breast carcinoma-resident immune cells, showing a continuum of activation and differentiation states for tumor-associated T cells and macrophages. Download →
Gene expression variability across cells and species shapes innate immunity
Hagai et al., Nature 2018
Used single cell and bulk RNA sequencing to chart the evolution of the innate immune response in mammals, identifying genes that were differentially expressed upon immune stimulation. Download →
Single cell analysis of fate-mapped macrophages reveals heterogeneity during atherosclerosis progression and regression
Lin et al., JCI Insight 2019
Used single cell RNA sequencing to characterize the cellular states of macrophages in atherosclerotic plaques, showing a spectrum of macrophage activation states. Download →
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High-throughput mapping of B cell receptor sequences to antigen specificity
Setliff et al., Cell 2019
Profiled PBMCs from two subjects with HIV, leveraging LIBRA-seq, a method to rapidly map paired heavy- and light-chain B-cell receptor (BCR) sequences to their corresponding antigens. Identified the antigen specificity of thousands of single B cells and discovered a novel broadly neutralizing antibody to HIV. Download →