WEBINAR

The Biology behind the PD-1 checkpoint blockade

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Presented by 10x Genomics and
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 Moderator

Chhavi Chauhan, Ph.D., E.L.S, 
Director of Scientific Outreach, American Society for Investigative Pathology
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Speaker

Arlene Sharpe, MD, PhD, Chair & Professor, Department of Immunology, Harvard Medical School



This webinar will focus on the functions of the PD-1 pathway and its inhibition as an immunotherapeutic approach. In addition, it will highlight the use of a CRISPR-based screening system for discovery of immunotherapy targets.

Key Learning Objectives: After attending this webinar, you will be able to:

  • Describe the functions of PD-1 inhibitory signals.
  • Understand the role of PD-1 pathway as a mediator of T cell exhaustion.
  • Appreciate the use of PD-1 checkpoint inhibitors in tumor prevention/management.
  • Understand the role of PD-1 signals in controlling primary influenza infection.
  • Describe the use of a CRISPR-based screening system for discovery of immunotherapy targets


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