Explore Innovative Techniques to Overcome Sample Challenges and Improve Data Quality in Clinical Trials
Join us for an exclusive webinar featuring two leading experts from Roche, showcasing groundbreaking advancements in single cell RNA sequencing (scRNA-seq) technologies, tailored for clinical trials. Whether you're working in immunology or oncology research, this webinar will equip you with cutting-edge methodologies for profiling complex cell populations—overcoming the challenges posed by sample viability, preservation, and analysis.
Key Topics You'll Learn:
- Comparative analysis of the 10x Single Cell Gene Expression Flex and other leading single-cell technologies for neutrophil transcriptome profiling
- Real-world applications of Chromium Single Cell Gene Expression Flex in tumor sample analysis
- Best practices for preserving RNA integrity in clinical samples, including FFPE tissues- How scRNA-seq can drive diagnostics, therapy development, and optimize clinical trials
Part 1: Transcriptome Profiling for Neutrophils in Clinical Trials by Emma Bell
Emma Bell will discuss the use of Chromium Single Cell Gene Expression Flex for profiling neutrophils in clinical trials. Neutrophils, a crucial part of the immune system, present unique challenges due to their low RNA content. Emma will share the results of a comparative study using Chromium Single Cell Gene Expression Flex and other technologies.The findings support Chromium Single Cell Gene Expression Flex as the ideal solution for neutrophil transcriptome profiling in clinical trials.
Key Highlights:
- Overcoming the challenges of working with neutrophil samples in clinical trials
- Comparing the performance of three scRNA-seq technologies
- How timely fixation is key to maintaining transcriptomic profiles
Part 2: The New Benchmark for Multisite Clinical Trials by Emilio Yangueez
Emilio Yangueez will introduce the Chromium Single Cell Gene Expression Flex as the new benchmark for multisite clinical trials. Focusing on oncology, Emilio will discuss how this protocol overcomes challenges in sample preservation and logistics, particularly with formalin-fixed paraffin-embedded (FFPE) tissues. A real-world case study from a clinical trial will demonstrate how this new protocol generates high-quality, reproducible genomic data from FFPE blocks.
Key Highlights:
- Addressing the challenges of scRNA-seq with limited biopsy material
- Benchmarking Chromium Flex against 10x Genomics' standard solutions
- A case study showcasing the benefits of fixed RNA chemistry in capturing robust genomic data from FFPE blocks
Why Attend?
This webinar is essential for clinical researchers, oncologists, and immunologists who are looking to leverage single cell RNA sequencing to drive innovation in diagnostics, therapeutics, and trial optimization. Our expert speakers from Roche will walk you through cutting-edge technologies, share practical tips, and offer real-world examples to improve your clinical research workflows.
Don’t miss your chance to learn from Roche’s senior scientists and stay ahead in the fast-evolving world of single cell genomics.
The webinar will consist of a ~40 minute presentation followed by a live Q&A session.
Speakers
Transcriptome Profiling for Neutrophils in Clinical Trials
Emma Bell
Senior Scientist
Roche
The New Benchmark for Multisite Clinical Trials
Emilio Yangüez
Senior Scientist
Roche
