Targeted Gene Expression

Focus on the genes that matter most

Overview

Comprehensively targeting relevant genes and biomarkers gives you a complete view of the biology most important to your research. With Targeted Gene Expression, you can combine the crucial insights enabled by single cell and spatial gene expression analysis with the efficiency and scalability of pre-designed or custom panels. Expand your traditional spatial gene profiling beyond a few genes of interest to all the relevant associated genes and pathways to discover new biomarkers or genes of interest with morphological context.
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Single Cell Gene Expression with Dual Index

Increase your confidence in assigned sample reads by mitigating index hopping effects with dual index libraries, now compatible with both whole transcriptome and targeted single cell gene expression.

New kits and compatibility
Note: Existing Single Cell Gene Expression v3.1 with Single Index kits remain available.

How do Single Cell Gene Expression v3.1 dual and single index libraries compare?
Read the tech note →

User guides and datasets
Single Cell Gene Expression with Dual Index user guide - Download now →
Single Cell Gene Expression with Dual Index dataset - View now →

Software
Use Cell Ranger 4.0 to process data from dual index libraries.  Learn more →

Product Discontinuation
For detailed information on product codes and last shipment dates, please see the linked sheet.
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Spatial Data
On-Demand Webinar

Introducing Targeted Spatial Gene Expression: Spatially Resolve All the Genes that Matter Most
Explore the potential of this focused approach to spatial gene expression with 10x Genomics product experts.
Watch now →

Highlights

10x product sheet Chromium and Visium Targeted Gene Expression
  • Focus on genes and pathways of interest using comprehensive, pre-designed human panels with the ability to add up to 200 custom genes, or design a fully custom panel*
  • Examine all relevant associated genes and pathways to expand your analysis beyond the limited targets enabled by traditional gene expression assays in tissue sections 
  • Transition seamlessly between whole transcriptome and targeted analysis from the same library preparation to validate discoveries or explore new hypotheses
  • Maximize your budget using targeted panels to cut sequencing costs by as much as 90%, or scale your studies with a 10-fold increase in sample throughput compared to whole transcriptome analysis

Download product sheet  |  Watch introductory webinar

*Please note that the use of Fully Custom Panels with Visium Spatial Gene Expression is not supported at this time.



Pre-designed Panels - Focus your research with a curated, ready-to-use solution

Get started quickly using pre-designed human panels to perform analysis of key genes and signaling pathways specific to your research questions. Customize each panel by adding up to 200 additional genes with our Custom Panel Designer.

Human Pan-Cancer Panel 1,253 genes spanning 33 cancer types
Product sheet | Gene List
Human Immunology Panel 1,056 genes probing immune-relevant cell types
Product sheet | Gene List
Human Gene Signature Panel 1,142 genes covering signaling pathways and drug targets
Product sheet | Gene List
Human Neuroscience Panel 1,186 genes encompassing neurodegenerative and neuroimmune pathways
Product sheet | Gene List

Custom Panel Designer - Focus your research with a user-friendly design tool

Use the Custom Panel Designer to create a fully custom* set of transcripts with 10–1,500 genes, or add up to 200 genes to pre-designed cancer, immunology, neuroscience, or gene signature panels. How does it work?
 Panel Designer - step 1
Sign up for a free and secure 10x Cloud account. Sign in to design panels and save them to your library. Come back later to edit or download your files.
 Panel Designer - step 3
Enter your desired gene names, IDs, or sequences. Within seconds, the optimized algorithm will design baits to target them. You’ll also get helpful guidance about the genes you’ve added and whether or not they are already included in the selected pre-designed panel.
Panel Designer - Step 4
Download your Bait Design file and order your custom panel from one of our Compatible Partners. The user guide will walk you through adding the custom baits to a pre-designed panel or using your panel on its own.
Get started building your panel today →

*Please note that the use of Fully Custom Panels with Visium Spatial Gene Expression is not supported at this time.


Explore Targeted Gene Expression

Targeted Gene Expression Page

Visit our Targeted Gene Expression product page to learn how you can start focusing on the biology most important to your research.

Explore Targeted Gene Expression →